Raspberry Pi and ppLOGGER Make a Low-Cost Chemiluminescence Detector
[Laena] and her colleagues at the La Trobe Institute for Molecular Science in Melbourne, Australia used a Raspberry Pi to make a low-cost electrochemiluminescence (ECL) detector to measure inflammation markers, which could be used to detect cardiovascular disease or sepsis early enough to give doctors a better chance at saving a patient’s life. ECL reactions emit light as a result of an electrically-activated chemical reaction, making them very useful for detecting biochemical markers in blood, saliva, or other biological samples. ECL setups are fundamentally fairly straightforward. The device includes a voltage reference generator to initiate the chemical reaction and a photomultiplier tube (PMT) to measure the emitted light. The PMT outputs a current which is then converted to a voltage using a transimpedance amplifier (TIA). That signal is then sampled by the DAQCplate expansion board and the live output can be viewed in ppLOGGER in real-time. Using the RPi allowed the tea...